Albumin is the most important binding and transport protein of the organism. The multitude functions of albumin are: Major contribution to plasma colloidal osmotic pressure, binding and transport of proteins, metal ions, bilirubin, free fatty acids, hormones, drugs, serving as an amino acid pool for protein synthesis and major antioxidant in plasma. Albumin measurements are made for monitoring patients with acute liver diseases, for suspected liver cirrhosis and monitoring patients with this disease, diagnosis of edematous status, prognosis of elderly, hospitalized patients. Colorimetric test for the quantitative determination of albumin in human serum and plasma.

Alkaline phosphatase activity is measured for diagnosis, monitoring and therapy control of liver, bone, parathyroid and intestinal diseases. Conditions with increased alkaline phosphatase levels are hepatobiliary diseases, primary and secondary bone diseases. Reduced alkaline phosphatase levels are found in familial hypophosphatasia, adynamic bone disease in dialysis patients, hypoparathyroidism, achondroplasia, pituitary dwarfism, chronic radiation sickness and malnutrition. Enzymatic color test for the quantitative determination of alkaline phosphatase in human serum and heparinised plasma.

Alpha-amylase activity is measured for detection of acute pancreatitis, chronic (relapsing) pancreatitis, obstruction of the pancreatic duct, detection of pancreatic involvement in abdominal disorders, surgical procedures, anorexia, bulimia, and parotitis. There is also a detectable increase in amylase after an endoscopic retrograde cholangiopancreatography (ERCP) procedure. Enzymatic color test for the quantitative determination of alpha-amylase in human serum, heparinised plasma and urine.

Anti-streptolysin-O are specific antibodies to streptolysin O, formed by an extracellular enzyme of group A ß-hemolytic streptococci. Streptococci are responsible for a variety of infections, including acute pharyngitis and other manifestations as glomerulonephritis, rheumatic fever, bacterial endocarditis and scarlet fever. Antibodies against streptolysin O are detectable one week to one month after a streptococcal infection. Laboratory results should always be interpretated in conjunction with other clinical findings. Latex enhanced immunoturbidimetric test for the quantitative determination of anti-streptolysin-O in human serum.

The apolipoproteins A1 are the main protein components of high-density lipoproteins (HDL-c). APO A1 has a role in the removal of excess cholesterol from the tissues and reduced levels of APO A1 have been observed in patients with coronary vascular disease. APO A1 measurements are frequently used in characterizing patients with genetic disorders that lead to low HDL cholesterol concentrations. Over the past several decades, decreased serum levels of high-density lipoprotein (HDL) and increased levels of low-density lipoprotein (LDL) have been associated with increased risk of coronary vascular disease. Immunoturbidimetric test for the quantitative determination of apolipoprotein A1 in human serum.

The apolipoproteins B are the main protein components of low density lipoproteins (LDL-c). APO B is necessary for the reaction with LDL receptors in the liver and on cell membranes and is thus involved in transporting cholesterol from the liver to the vessel cells. Elevated levels of APO B are frequently found in atherosclerotic vascular changes and are a risk factor for atherosclerosis. Over the past several decades, decreased serum levels of high-density lipoprotein (HDL) and increased levels of low-density lipoprotein (LDL) have been associated with increased risk of coronary vascular disease. Immunoturbidimetric test for the quantitative determination of apolipoprotein B in human serum.

Bilirubin total is a laboratory test for the diagnosis, differential diagnosis and therapy control of jaundice, caused by liver, hemolytic, hematological, and metabolic disorders, including hepatitis and gall bladder block. Colorimetric test for the quantitative determination of bilirubin total in human serum and plasma.

Cholinesterase activity measurements are used as a test of liver function in patients with acute and chronic hepatitis, liver sclerosis, as an indicator of insecticide poisoning and as a means to investigate atypical variants of the enzyme. A decreased level of enzyme activity is an indication of any of the above conditions. CHE is also used to identify patients with low enzyme activity before administration of muscle relaxants of the succinylcholine type. CHE activity is regarded as the most important indicator of degree of intoxication by organophosphorus pesticide. Enzymatic colorimetric test for the quantitative determination of Cholinesterase in human serum and plasma.

Direct bilirubin (DBIL) is a helpful marker for hepatic and post-hepatic jaundice, whereas pre-hepatic jaundice is primarily associated with an increase of indirect bilirubin. Increased direct bilirubin concentrations are found in acute and chronic viral hepatitis, liver cirrhosis, hepatocellular carcinoma, extrahepatic cholestasis, liver transplant rejection, and congential disorders like Dubin-Johnson and Rotor syndrome. Colorimetric test for the quantitative determination of bilirubin direct in human serum and plasma.

Creatine kinase activity and the activity of its isoenzymes is measured for diagnosis and therapy control of myocardial infarction, myocarditis, cerebrovascular accidents, skeletal muscular dystrophies, and cardiac and skeletal muscle diseases. Creatine kinase activity is also measured for monitoring the treatment of cancer patients. Enzymatic UV test for the quantitative determination of creatine kinase in human serum and plasma.

Calcium measurements are used in the diagnosis and treatment of parathyroid disease, a variety of bone diseases, chronic renal disease and tetany (intermittent muscular contractions or spasms). Colorimetric test for the quantitative determination of calcium total in human serum and heparinised plasma.

Total cholesterol (CHOL) measurements are used for diagnosis and therapy control of atherosclerotic coronary vascular disease and metabolic disorders such as dyslipidemia and liver diseases. The concentration of total cholesterol in serum or plasma is influenced by different factors like age, sex, diet and physical activity. Colorimetric enzymatic test for the quantitative determination of total cholesterol in human serum and plasma.

Creatinine (CREA) is a product of the muscle metabolism. Creatinine measurements are used for diagnosis and therapy control of renal diseases and monitoring renal dialysis. The concentration of creatinine is influenced by age, body weight, and sex. Urea/BUN and creatinine determinations are frequently performed together in the differential diagnosis of kidney function. Colorimetric (Jaffé) and enzymatic tests for the quantitative determination of creatinine in human serum, plasma and urine. Creatinine concentration in urine is a calculation basis for other urine analytes.

CK-MB is a rapidly appearing biomarker in case of a myocardial infarction. The rise in activity of CK-MB depends on the size of the cardiac muscle damage. Homogeneous test for the quantitative determination of CK-MB in human serum and plasma.

C-reactive protein (CRP) is an acute phase protein which is synthesised in the liver. Inflammatory processes, bacterial infections, polytrauma, myocardial infarction and certain other diseases (e.g. M. Bechterew, M. Crohn, rheumatoid arthritis) are accompanied by a significant increase of the CRP concentration. Following surgery the CRP concentration will also be elevated. It has been shown that persistently increased CRP levels may indicate a bad prognosis for the patients outcome. Therefore monitoring of the CRP concentration can be helpful to initiate necessary treatment in time. Immunoturbidimetric test for the quantitative determination of C-reactive protein in human serum and plasma.

Complement C3 (C3c) is the central point of the classic and alternative complement pathway. C3c is a constituent of C5 convertase. On activation split products of C3c have important biological functions. C3b is an opsonin and involved in immune adherence, C3a is an anaphylatoxin and a chemotoxin. C3c behaves also like an acute phase protein, therefore increased levels may be found in acute inflammatory reactions. Decreased levels are reported in complex diseases, recurrent immune infections with pyrogenic bacteria, various glomerulonephritides and in congenital deficiencies. Immunoturbidimetric test for the quantitative determination of complement C3 (C3c) in human serum.

Cystatin-C is as an excellent biomarker of the GFR and used for diagnosis and treatment of renal diseases. Cystatin-C is freely filtered through the glomerular membrane of the kidney and reabsorbed and degraded in the kidney cells. The concentration of Cystatin-C is only dependent on the glomerular filtration rate (GFR) itself. Latex enhanced immunoturbidimetric test for the quantitative determination of Cystatin-C in human serum.